|Other Accession||NM_005613, NP_005604|
|Reactivity||Human, Mouse, Rat, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Sheep, Bovine, Dog|
|Alias Symbol||MGC2124, MGC60244, RGP4, SCZD9|
|Other Names||Regulator of G-protein signaling 4, RGP4, RGS4, RGS4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RGS4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RGS4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.|
|Tissue Location||Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum|
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Provided below are standard protocols that you may find useful for product applications.
Ishii,M., (2005) Biochem. Biophys. Res. Commun. 338 (2), 839-846 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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