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Rab10 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Rab10 antibody - C-terminal region AI10191
    Rab1 antibody - C-terminal region (AI1191) validated by WB using Mouse Kidney lysate at 1μg/ml.
  • WB - Rab10 antibody - C-terminal region AI10191

    Sample Type: 1. Human Cervical Cancer cell lysate

    2. Monkey Fibroblast cell lysate

    3. Human Cervical Cancer Cell transfected with mouse Rab1-GFP (15ug)
    Primary Dilution: 1:1
    Secondary Antibody: goat anti-Rabbit
    Secondary Dilution: 1:4,
    Submitted by:
      Dr. Jakob Szwedo, Dr. Lupashin's Lab
    University of Arkansas for Medical Sciences

    See Customer Feedback tab for detailed information.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P61027
Other Accession NM_016676, NP_057885
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Sheep, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Sheep, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 22kDa
Additional Information
Gene ID 19325
Alias Symbol AW107754
Other Names Ras-related protein Rab-10, Rab10
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rab10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRab10 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rab10
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. Finally, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.
Cellular Location Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane. Endosome membrane Recycling endosome membrane. Cytoplasmic vesicle, phagosome membrane. Cell projection, cilium. Endoplasmic reticulum membrane. Note=Associates with SLC2A4/GLUT4 storage vesicles (By similarity). Localizes to the base of the cilium. Transiently associates with phagosomes (By similarity) Localizes to the endoplasmic reticulum at domains of new tubule growth (By similarity).
Research Areas
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$ 293.00
Cat# AI10191
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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