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Hes1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Hes1 antibody - C-terminal region AI10293
    WB Suggested Anti-Hes1 Antibody Titration: .2-1 μg/ml
    ELISA Titer: 1:125
    Positive Control: Rat Kidney
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q04666
Other Accession NM_024360, NP_077336
Reactivity Human, Mouse, Rat, Pig, Bovine
Predicted Human, Mouse, Rat, Pig, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Additional Information
Gene ID 29577
Alias Symbol Hes1
Other Names Transcription factor HES-1, Hairy and enhancer of split 1, Hairy-like protein, RHL, Hes1, Hes-1, Hl
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Hes1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHes1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hes1
Synonyms Hes-1, Hl
Function Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Cellular Location Nucleus.
Tissue Location Present in all tissues examined but highest in epithelial cells and in mesoderm-derived tissues such as embryonal muscle cells
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$ 293.00
Cat# AI10293
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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