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Hes1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q04666 |
| Other Accession | NM_024360, NP_077336 |
| Reactivity | Human, Mouse, Rat, Pig, Bovine |
| Predicted | Human, Mouse, Rat, Pig, Bovine, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 30kDa |
| Gene ID | 29577 |
|---|---|
| Alias Symbol | Hes1 |
| Other Names | Transcription factor HES-1, Hairy and enhancer of split 1, Hairy-like protein, RHL, Hes1, Hes-1, Hl |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Hes1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Hes1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Hes1 |
|---|---|
| Synonyms | Hes-1, Hl |
| Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'- CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Present in all tissues examined but highest in epithelial cells and in mesoderm-derived tissues such as embryonal muscle cells |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI10293
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