Rnf166 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q3U9F6 |
Other Accession | NM_001033142, NP_001028314 |
Reactivity | Human, Mouse, Rat, Zebrafish, Horse, Bovine, Dog |
Predicted | Mouse, Chicken, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26kDa |
Gene ID | 68718 |
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Alias Symbol | 1110031E24Rik, AW555115, Zfp313l |
Other Names | RING finger protein 166, Rnf166 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Rnf166 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Rnf166 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Rnf166 |
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Function | E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Also plays a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys- 29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q96A37}. |
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