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Rnf166 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Rnf166 antibody - middle region AI10316
    WB Suggested Anti-Rnf166 Antibody
    Titration: 1. μg/ml
    Positive Control: Mouse Pancreas
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q3U9F6
Other Accession NM_001033142, NP_001028314
Reactivity Human, Mouse, Rat, Zebrafish, Horse, Bovine, Dog
Predicted Mouse, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Additional Information
Gene ID 68718
Alias Symbol 1110031E24Rik, AW555115, Zfp313l
Other Names RING finger protein 166, Rnf166
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rnf166 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRnf166 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rnf166
Function E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Also plays a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys- 29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q96A37}.
Research Areas
Citations (0)
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$ 389.00
Cat# AI10316
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