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Snf8 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Snf8 antibody - N-terminal region AI10426
    WB Suggested Anti-Snf8 Antibody
    Titration: 1. μg/ml
    Positive Control: Rat Liver
  • IHC - Snf8 antibody - N-terminal region AI10426
    Rabbit Anti-Snf8 Antibody

    Catalog Number: AI1426

    Formalin Fixed Paraffin Embedded Tissue: Human Adult liver
    Observed Staining: Cytoplasmic

    Primary Antibody
    Concentration: 1:1

    Secondary Antibody: Donkey anti-Rabbit-Cy2/3

    Secondary Antibody
    Concentration: 1:2

    Magnification: 2X

    Exposure Time: .5 – 2. sec

    Protocol located in Reviews and Data.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5RK19
Other Accession NM_001007804, NP_001007805
Reactivity Human, Mouse, Rat, Zebrafish, Goat, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Additional Information
Gene ID 287645
Alias Symbol D11moh34, MGC105799, RGD1310144
Other Names Vacuolar-sorting protein SNF8, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22, Snf8, Eap30
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Snf8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSnf8 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Snf8
Synonyms Eap30
Function Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization (By similarity). Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.
Cellular Location Cytoplasm. Endosome membrane. Nucleus. Late endosome membrane. Note=Recruited to the endosome membrane to participate in vesicle formation.
Research Areas
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$ 293.00
Cat# AI10426
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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