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POU3F1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q03052 |
| Other Accession | NM_002699, NP_002690 |
| Reactivity | Human, Mouse, Rat, Bovine, Dog |
| Predicted | Mouse, Pig, Bovine, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Gene ID | 5453 |
|---|---|
| Alias Symbol | OCT6, OTF6, SCIP |
| Other Names | POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP, POU3F1, OCT6, OTF6 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-POU3F1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | POU3F1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POU3F1 |
|---|---|
| Synonyms | OCT6, OTF6 |
| Function | Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3') (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). Acts as a transcriptional repressor of myelin-specific genes (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P21952}. |
| Tissue Location | Expressed in embryonal stem cells and in the developing brain |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Sumiyama,K., et al., (1998) Mamm. Genome 9 (2), 180-181Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Hashimoto, Y. et al. Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer. Breast Cancer Res. Treat. 145, 101-11 (2014). IHC, Bovine, Dog, Rabbit, Guinea pig, Rat, Mouse, Human24671357
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