|Other Accession||NM_024814, NP_079090|
|Reactivity||Human, Mouse, Rat, Zebrafish, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Bovine, Guinea Pig, Dog|
|Alias Symbol||FLJ23109, HAKAI, MGC163401, MGC163403, RNF188|
|Other Names||E3 ubiquitin-protein ligase Hakai, 6.3.2.-, Casitas B-lineage lymphoma-transforming sequence-like protein 1, RING finger protein 188, c-Cbl-like protein 1, CBLL1, HAKAI, RNF188|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CBLL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CBLL1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation.|
|Cellular Location||Nucleus speckle. Nucleus, nucleoplasm|
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Provided below are standard protocols that you may find useful for product applications.
Fletcher,B.S., J. Cell. Sci. 117 (PT 7), 989-998 (2004)Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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