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S100b antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - S100b antibody - N-terminal region AI10571
    WB Suggested Anti-S1b Antibody
    Titration: 1. μg/ml
    Positive Control: Rat Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04631
Other Accession NM_013191, NP_037323
Reactivity Human, Mouse, Rat, Goat, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 10kDa
Additional Information
Gene ID 25742
Alias Symbol MGC93559, S100P
Other Names Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, S100b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-S100b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsS100b antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S100b
Function Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Cellular Location Cytoplasm. Nucleus
Tissue Location Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues
Citations (0)

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$ 293.00
Cat# AI10571
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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