|Application ||WB, IHC|
|Other Accession||NM_001449, NP_001440|
|Reactivity||Human, Mouse, Rat, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Sheep, Bovine, Guinea Pig, Dog|
|Alias Symbol||KYOT, SLIM, FHL-1, FHL1A, FHL1B, FLH1A, SLIM1, XMPMA, SLIM-1, SLIMMER|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-FHL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FHL1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
McGrath,M.J., et al., (2003) Am. J. Physiol., Cell Physiol. 285 (6), C1513-C1526Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Windpassinger, C. et al. An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1. Am. J. Hum. Genet. 82, 88-99 (2008). WB, IHC, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit18179888Quinzii, C. M. et al. X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1. Am. J. Hum. Genet. 82, 208-13 (2008). WB, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit18179901Schoser, B. et al. Consequences of mutations within the C terminus of the FHL1 gene. Neurology 73, 543-51 (2009). WB, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit19687455Gueneau, L. et al. Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy. Am. J. Hum. Genet. 85, 338-53 (2009). IHC, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit19716112Sharma, P., Shathasivam, T., Ignatchenko, V., Kislinger, T. & Gramolini, A. O. Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis. Mol. Biosyst. 7, 1185-96 (2011). WB, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit21246116Dong, R. et al. Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures. Cell. Immunol. 272, 1-10 (2011). WB, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit22053194Koike, K. et al. High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer. Int. J. Oncol. 42, 141-50 (2013). WB, IHC, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit23123766Fujii, T. et al. A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles. J. Neurol. Sci. 343, 206-10 (2014). WB, Mouse, Human, Sheep, Dog, Bovine, Horse, Guinea pig, Rat, Rabbit24928078
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