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Uhrf2 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Uhrf2 antibody - N-terminal region AI10727

    WB Suggested Anti-Uhrf2 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
  • WB - Uhrf2 antibody - N-terminal region AI10727

    WB Suggested Anti-Uhrf2 Antibody
    Positive Control: Lane 1: 60ug HCT116 lysate
    Primary Antibody Dilution : 1:1000
    Secondary Antibody : Anti rabbit-HRP
    Secondry Antibody Dilution : 1:5,000
    Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7TMI3
Other Accession NM_144873, NP_659122
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Dog
Predicted Human, Mouse, Rabbit, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 90kDa
Additional Information
Gene ID 109113
Alias Symbol 2310065A22Rik, AI426270, AW214556, D130071B19Rik, Nirf
Other Names E3 ubiquitin-protein ligase UHRF2, 6.3.2.-, NIRF, Np95-like ring finger protein, Nuclear protein 97, Nuclear zinc finger protein Np97, Ubiquitin-like PHD and RING finger domain-containing protein 2, Ubiquitin-like-containing PHD and RING finger domains protein 2, Uhrf2, Nirf
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Uhrf2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUhrf2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Uhrf2
Synonyms Nirf
Function E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131 (By similarity). E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00358, ECO:0000269|PubMed:21598301}. Note=Enriched at pericentric heterochromatin (PH). This localization is dependent on the interaction with H3K9me3
Research Areas
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$ 293.00
Cat# AI10727
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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