|Application ||WB, IHC|
|Other Accession||NM_002249, NP_002240|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Bovine|
|Alias Symbol||SK3, hSK3, SKCA3, KCa2.3|
|Other Names||Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3, KCNN3, K3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-KCNN3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||KCNN3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Kolski-Andreaco,A., et al., (2004) J. Biol. Chem. 279 (8), 6893-6904Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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