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Scn1b Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q00954 |
| Other Accession | NM_017288, NP_058984 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Pig, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23kDa |
| Gene ID | 29686 |
|---|---|
| Other Names | Sodium channel subunit beta-1, Scn1b |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Scn1b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Scn1b Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Scn1b |
|---|---|
| Function | Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle (PubMed:1375395, PubMed:8282123, PubMed:8021275, PubMed:15178439, PubMed:28012039). Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation (PubMed:1375395, PubMed:8282123, PubMed:8021275, PubMed:15178439, PubMed:28012039). Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A (PubMed:1375395, PubMed:8282123, PubMed:8021275, PubMed:15178439, PubMed:28012039). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q07699} Perikaryon {ECO:0000250|UniProtKB:P97952}. Cell projection {ECO:0000250|UniProtKB:P97952}. Cell projection, axon. Note=Detected at nodes of Ranvier on the sciatic nerve. |
| Tissue Location | Detected in brain (at protein level) (PubMed:11470829). Expressed in brain, heart, skeletal muscle and spinal cord (PubMed:1375395, PubMed:8282123) |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI10854
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