|Other Accession||NM_053023, NP_444251|
|Reactivity||Human, Mouse, Rat, Rabbit, Bovine, Horse, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Bovine, Horse, Dog|
|Alias Symbol||PZF, DMS-8, DSM-8, FKSG11, ZFP-91, ZNF757|
|Other Names||E3 ubiquitin-protein ligase ZFP91, 6.3.2.-, Zinc finger protein 757, Zinc finger protein 91 homolog, Zfp-91, ZFP91, ZNF757|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ZFP91 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZFP91 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Atypical E3 ubiquitin-protein ligase that mediates 'Lys- 63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non- canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.|
|Tissue Location||Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific|
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Provided below are standard protocols that you may find useful for product applications.
Unoki,M., et al., (2003) Int. J. Oncol. 22 (6), 1217-1223Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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