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ZBP1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - ZBP1 antibody - middle region AI11021

    WB Suggested Anti-ZBP1 Antibody Titration: 5.0 μg/ml
    Positive Control: HepG2 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H171
Other Accession NM_030776, NP_110403
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 81030
Alias Symbol DAI, DLM1, DLM-1, C20orf183
Other Names Z-DNA-binding protein 1, Tumor stroma and activated macrophage protein DLM-1, ZBP1, C20orf183, DLM1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-ZBP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsZBP1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBP1
Synonyms C20orf183, DLM1
Function Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
Tissue Location Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen Expressed to a lesser extent in thymus, lung and liver
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$ 232.00
Cat# AI11021
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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