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Elf3 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Elf3 antibody - middle region AI11047

    WB Suggested Anti-Elf3 Antibody Titration: 0.2-1 μg/ml
    Positive Control: SP2/0 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q3UPW2
Other Accession NM_007921, NP_031947
Reactivity Human, Mouse, Rat, Bovine, Dog
Predicted Mouse, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Additional Information
Gene ID 13710
Alias Symbol ESE-1, ESX, jen
Other Names ETS-related transcription factor Elf-3, E74-like factor 3, Epithelial-restricted with serine box, Epithelium-restricted Ets protein ESX, Epithelium-specific Ets transcription factor 1, ESE-1, Elf3 {ECO:0000312|MGI:MGI:1101781}, Ert, Esx, Jen
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Elf3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsElf3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Elf3 {ECO:0000312|MGI:MGI:1101781}
Synonyms Ert, Esx, Jen
Function Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity (By similarity). Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway (By similarity). May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P78545}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237, ECO:0000269|PubMed:16516205}
Tissue Location Expressed in small intestine, colon, lung, kidney and uterus. Also expressed in the corneal epithelium and conjunctiva of the developing and adult eye. Not detected in liver, spleen, thymus, brain, heart, skeletal muscle or ovary
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$ 293.00
Cat# AI11047
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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