|Other Accession||NM_011541, NP_035671|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Dog|
|Predicted||Human, Mouse, Rat, Chicken|
|Alias Symbol||MGC103154, S-II|
|Other Names||Transcription elongation factor A protein 1, Transcription elongation factor S-II protein 1, Transcription elongation factor TFIIS.o, Tcea1, Tceat|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Tcea1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Tcea1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.|
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