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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   Nr5a1 Antibody - C-terminal region   

Nr5a1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Nr5a1 Antibody - C-terminal region AI11227

    Host: Rabbit
    Target Name: Nr5a1
    Sample Tissue: Mouse Lung lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P33242
Other Accession NM_139051, NP_620639
Reactivity Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine
Predicted Human, Mouse, Rat, Rabbit, Sheep, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Additional Information
Gene ID 26423
Alias Symbol Ad4BP, ELP, ELP-3, Ftz-F1, Ftzf1, SF-1, SF1
Other Names Steroidogenic factor 1, SF-1, STF-1, Adrenal 4-binding protein, Embryonal LTR-binding protein, ELP, Embryonal long terminal repeat-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP, Steroid hydroxylase positive regulator, Nr5a1, Ftzf1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Nr5a1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNr5a1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nr5a1
Synonyms Ftzf1
Function Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO- NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity (By similarity). Transcription repressor of the Moloney leukemia virus long terminal repeat in undifferentiated murine embryonal carcinoma cells. Binds phosphatidylcholine and phospholipids with a phosphatidylinositol (PI) headgroup, in particular phosphatidyl(3,4)bisphosphate, phosphatidyl(3,5)bisphosphate and phosphatidyl(3,4,5)triphosphate. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Cellular Location Nucleus.
Research Areas
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$ 293.00
Cat# AI11227
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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