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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SCN3B antibody - N-terminal region   

SCN3B antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - SCN3B antibody - N-terminal region AI11300

    WB Suggested Anti-SCN3B Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:12500
    Positive Control: Human brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NY72
Other Accession NM_018400, NP_060870
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 24kDa
Additional Information
Gene ID 55800
Alias Symbol HSA243396, SCNB3
Other Names Sodium channel subunit beta-3, SCN3B, KIAA1158
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SCN3B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSCN3B antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCN3B
Synonyms KIAA1158
Function Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in the atrium.
Research Areas
Citations (0)

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Kimura,K., et al., (2006) Genome Res. 16 (1), 55-65Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Hu, D. et al. A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype. Circ. Cardiovasc. Genet. 2, 270-8 (2009). WB, Mouse, Human, H, Rabbit, Bovine, Rat, Dog, Guinea pig20031595Ho, C., Zhao, J., Malinowski, S., Chahine, M. & O’Leary, M. E. Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons. J. Biol. Chem. 287, 15044-53 (2012). WB, Mouse, Human, H, Rabbit, Bovine, Rat, Dog, Guinea pig22408255

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$ 293.00
Cat# AI11300
(40 western blots)
Availability: 2-3 days
Bulk Size
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