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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   Eed antibody - C-terminal region   

Eed antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Eed antibody - C-terminal region AI11405

    WB Suggested Anti-Eed Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Muscle
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9WVH3
Other Accession NM_018789, NP_061259
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 54601
Alias Symbol afx, Afxh, Mllt7
Other Names Forkhead box protein O4, Afxh, Fork head domain transcription factor AFX1, Foxo4, Afx, Afx1, Fkhr3, Mllt7
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Eed antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsEed antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Foxo4
Synonyms Afx, Afx1, Fkhr3, Mllt7
Function Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity). Represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.
Cellular Location Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm Dephosphorylation triggers nuclear translocation Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm (By similarity).
Tissue Location Strongly expressed in brown adipose tissue and weakly in white adipose tissue (at protein level). Expressed in skeletal muscle.
Research Areas
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$ 293.00
Cat# AI11405
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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