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> home > Products > Primary Antibodies > Antibody Collections > Ubiquitin E3 Ligases (RING Domain) Antibodies > TRIM62 antibody - N-terminal region
TRIM62 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9BVG3 |
| Other Accession | NM_018207, NP_060677 |
| Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine |
| Predicted | Human, Mouse, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54kDa |
| Gene ID | 55223 |
|---|---|
| Alias Symbol | DEAR1 |
| Other Names | E3 ubiquitin-protein ligase TRIM62, 6.3.2.-, Tripartite motif-containing protein 62, TRIM62 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-TRIM62 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TRIM62 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRIM62 {ECO:0000303|PubMed:23402750, ECO:0000312|HGNC:HGNC:25574} |
|---|---|
| Function | E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C- type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways (PubMed:26488816). E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2 (PubMed:23402750). |
| Cellular Location | Cytoplasm |
Research Areas
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$ 339.00
Cat# AI11535
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