|Other Accession||NM_138632, NP_619538|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Horse, Bovine, Dog|
|Alias Symbol||DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4|
|Other Names||TRIO and F-actin-binding protein, Protein Tara, Trio-associated repeat on actin, TRIOBP, KIAA1662, TARA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TRIOBP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TRIOBP antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin. The localized formation of TARA and TRIO complexes coordinates the amount of F-actin present in stress fibers. May also serve as a linker protein to recruit proteins required for F-actin formation and turnover.|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton Note=Localized to F-actin in a periodic pattern|
|Tissue Location||Widely expressed. Highly expressed in heart and placenta. Isoform 3 is expressed in fetal brain, retina and cochlea but is not detectable in the other tissues|
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Provided below are standard protocols that you may find useful for product applications.
Yu,J., (2008) Biochem. Biophys. Res. Commun. 367 (4), 805-812 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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