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Kbtbd5 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Kbtbd5 antibody - N-terminal region AI11643

    WB Suggested Anti-Kbtbd5 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Brain
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9D783
Other Accession NM_028202, NP_082478
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Rabbit, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 69kDa
Additional Information
Gene ID 72330
Alias Symbol 2310024D23Rik, Kbtbd5
Other Names Kelch-like protein 40, Kelch repeat and BTB domain-containing protein 5, Klhl40, Kbtbd5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Kbtbd5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKbtbd5 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Klhl40 {ECO:0000312|MGI:MGI:1919580}
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development (PubMed:25940086). The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (PubMed:25940086). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (PubMed:24960163).
Cellular Location Cytoplasm. Cytoplasm, myofibril, sarcomere, A band Cytoplasm, myofibril, sarcomere, I band
Tissue Location Specifically expressed in skeletal muscles in embryonic, neonatal and adults (PubMed:24960163, PubMed:25940086) Expressed in various types of muscles, including extensor digitorum longus, gastrocnemius, soleus, diaphragm, masseter and heart (at protein level). Not detected in brain, liver and lung (at protein level).
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$ 389.00
Cat# AI11643
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