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INSIG1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - INSIG1 antibody - middle region AI11691

    WB Suggested Anti-INSIG1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Human Muscle
  • WB - INSIG1 antibody - middle region AI11691

    Host: Rabbit
    Target Name: WT1
    Sample Tissue: 721_B
    Antibody Dilution: 1.0μg/mlINSIG2 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5U4
Other Accession NM_016133, NP_057217
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Sheep, Horse, Bovine, Dog
Predicted Human, Rabbit, Pig, Chicken, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Additional Information
Gene ID 51141
Alias Symbol MGC26273, INSIG1
Other Names Insulin-induced gene 2 protein, INSIG-2, INSIG2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-INSIG1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsINSIG1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Li,C.G., (2008) Int. J. Cancer 123 (2), 273-282 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11691
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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