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RPL13 antibody - C-terminal region
Rabbit Polyclonal Antibody
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P26373 |
| Other Accession | NM_000977, NP_000968 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24kDa |
| Gene ID | 6137 |
|---|---|
| Alias Symbol | BBC1, D16S444E, FLJ27453, FLJ27454, MGC117342, MGC71373, L13, D16S44E |
| Other Names | 60S ribosomal protein L13, Breast basic conserved protein 1, RPL13, BBC1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RPL13 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RPL13 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPL13 |
|---|---|
| Synonyms | BBC1 |
| Function | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:31630789, PubMed:23636399, PubMed:32669547). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs (PubMed:31630789). Plays a role in bone development (PubMed:31630789). |
| Cellular Location | Cytoplasm |
| Tissue Location | Higher levels of expression in benign breast lesions than in carcinomas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Bi,W., (2002) Genome Res. 12 (5), 713-728Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Hartl, T. A. et al. Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila. Genetics 194, 101-15 (2013). WB, Human, Mouse, Rat, Dog, Bovine, H, Rabbit, Guinea pig, Zebrafish23436180
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