|Other Accession||NM_003769, NP_003760|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Zebrafish, Dog|
|Alias Symbol||SRp30c, SFRS9|
|Other Names||Serine/arginine-rich splicing factor 9, Pre-mRNA-splicing factor SRp30C, Splicing factor, arginine/serine-rich 9, SRSF9, SFRS9, SRP30C|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SFRS9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SFRS9 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.|
|Cellular Location||Nucleus. Note=Cellular stresses such as heat shock may induce localization to discrete nuclear bodies termed SAM68 nuclear bodies (SNBs), HAP bodies, or stress bodies Numerous splicing factors including SRSF1/SFRS1/SF2, SRSF7/SFRS7, SAFB and KHDRBS1/SAM68 accumulate at these structures, which may participate in the post-transcriptional regulation of mRNAs in stressed cells|
|Tissue Location||Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Paradis,C., (2007) RNA 13 (8), 1287-1300 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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