|Application ||WB, IHC|
|Other Accession||NM_006397, NP_006388|
|Alias Symbol||JUNB, RNASEHI, RNHIA, RNHL, AGS4|
|Other Names||Ribonuclease H2 subunit A, RNase H2 subunit A, 220.127.116.11, Aicardi-Goutieres syndrome 4 protein, AGS4, RNase H(35), Ribonuclease HI large subunit, RNase HI large subunit, Ribonuclease HI subunit A, RNASEH2A, RNASEHI, RNHIA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RNASEH2A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RNASEH2A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.|
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Provided below are standard protocols that you may find useful for product applications.
Frank,P., (1998) Proc. Natl. Acad. Sci. U.S.A. 95 (22), 12872-12877 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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