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LSM6 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - LSM6 antibody - middle region AI11787

    WB Suggested Anti-LSM6 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: HCT15 cell lysate
    LSM6 is supported by BioGPS gene expression data to be expressed in HCT15
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62312
Other Accession NM_007080, NP_009011
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Yeast, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 9kDa
Additional Information
Gene ID 11157
Alias Symbol YDR378°C
Other Names U6 snRNA-associated Sm-like protein LSm6, LSM6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-LSM6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLSM6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LSM6
Function Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
Cellular Location Cytoplasm. Nucleus
Research Areas
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$ 293.00
Cat# AI11787
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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