|Other Accession||NM_017619, NP_060089|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Dog|
|Alias Symbol||FLJ20008, FLJ25070, KIAA183, RBM40, RNP|
|Other Names||RNA-binding protein 40, RNA-binding motif protein 40, RNA-binding region-containing protein 3, U11/U12 small nuclear ribonucleoprotein 65 kDa protein, U11/U12 snRNP 65 kDa protein, U11/U12-65K, RNPC3, KIAA1839, RBM40, RNP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RNPC3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RNPC3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1839, RBM40, RNP|
|Function||Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.|
|Tissue Location||Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Benecke,H., (2005) EMBO J. 24 (17), 3057-3069 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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