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>   home   >   Products   >   Primary Antibodies   >   TNRC6A antibody - N-terminal region   

TNRC6A antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - TNRC6A antibody - N-terminal region AI11827

    WB Suggested Anti-TNRC6A Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: MCF7 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NDV7
Other Accession NM_014494, NP_055309
Reactivity Human, Mouse, Horse, Dog
Predicted Mouse, Rat, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 210kDa
Additional Information
Gene ID 27327
Alias Symbol CAGH26, DKFZp666E117, FLJ22043, GW1, GW182, KIAA1460, MGC75384, TNRC6
Other Names Trinucleotide repeat-containing gene 6A protein, CAG repeat protein 26, EMSY interactor protein, GW182 autoantigen, Protein GW1, Glycine-tryptophan protein of 182 kDa, TNRC6A, CAGH26, KIAA1460, TNRC6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TNRC6A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTNRC6A antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAGH26, KIAA1460, TNRC6
Function Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
Cellular Location Cytoplasm, P-body Note=Mammalian P-bodies are also known as GW bodies (GWBs)
Tissue Location Ubiquitous..
Citations (0)

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Eulalio,A., (2008) Nat. Struct. Mol. Biol. 15 (4), 346-353 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Bukong, T. N., Hou, W., Kodys, K. & Szabo, G. Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology 57, 70-80 (2013). WB, H, Mouse, Human, Dog22898980

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$ 293.00
Cat# AI11827
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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