Wdr8 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9JM98 |
Other Accession | NM_021499, NP_067474 |
Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Chicken |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 52kDa |
Gene ID | 59002 |
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Alias Symbol | 2610044M17Rik, 5330425N03Rik, Dd57, Wrap73, Wdr8 |
Other Names | WD repeat-containing protein WRAP73, WD repeat-containing protein 8, WD repeat-containing protein antisense to TP73 gene, Wrap73, Dd57, Wdr8 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Wdr8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Wdr8 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Wrap73 |
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Synonyms | Dd57, Wdr8 |
Function | The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (By similarity). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9P2S5}. Note=Enriched in the proximal end of the mother centriole. During ciliogenesis also associated with the basal body of the adjacent centriole (By similarity) {ECO:0000250|UniProtKB:Q9P2S5} |
Tissue Location | Ubiquitous. |
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