Cdc25b Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P30306 |
Other Accession | NM_023117, NP_075606 |
Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 65kDa |
Gene ID | 12531 |
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Alias Symbol | AI604853 |
Other Names | M-phase inducer phosphatase 2, 3.1.3.48, Dual specificity phosphatase Cdc25B, Cdc25b, Cdc25m2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Cdc25b antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Cdc25b Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Cdc25b |
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Synonyms | Cdc25m2 |
Function | Tyrosine protein phosphatase which functions as a dosage- dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2- dependent manner. The three isoforms seem to have a different level of activity. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:P30305}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:P30305} |
Tissue Location | Expressed predominantly in spleen, lung, heart, brain, intestine, and muscle. |
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