|Other Accession||NM_001024351, NP_001019522|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine|
|Predicted||Human, Mouse, Rat|
|Other Names||Apolipoprotein F, Apo-F, Liver regeneration-related protein LRRG151, Apof|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Apof antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Apof antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII (By similarity).|
|Cellular Location||Secreted. EMBL; BC088170; AAH88170.1; -; mRNA EMBL; AY325229; AAP92630.1; -; mRNA RefSeq; NP_001019522.1; NM_001024351.1 UniGene; Rn.101696; - STRING; 10116.ENSRNOP00000049259; - PaxDb; Q5M889; - PRIDE; Q5M889; - Ensembl; ENSRNOT00000041341; ENSRNOP00000049259; ENSRNOG00000033619 GeneID; 500761; - KEGG; rno:500761; - UCSC; RGD:1560713; rat CTD; 319; - RGD; 1560713; Apof eggNOG; ENOG410J2UW; Eukaryota eggNOG; ENOG4112458; LUCA GeneTree; ENSGT00500000045104; - HOGENOM; HOG000034007; - HOVERGEN; HBG050551; - InParanoid; Q5M889; - OMA; VWALQLQ; - OrthoDB; EOG091G0O2P; - PhylomeDB; Q5M889; - TreeFam; TF338778; - PRO; PR:Q5M889; - Proteomes; UP000002494; Chromosome 7 Bgee; ENSRNOG00000033619; - GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-KW GO; GO:0034362; C:low-density lipoprotein particle; IEA:UniProtKB-KW GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW InterPro; IPR026114; APOF PANTHER; PTHR15011; PTHR15011; 1 Pfam; PF15148; Apolipo_F; 1 2: Evidence at transcript level; Cholesterol metabolism; Cleavage on pair of basic residues; Complete proteome; HDL; LDL; Lipid metabolism; Lipid transport; Reference proteome; Secreted; Signal; Steroid metabolism; Sterol metabolism; Transport SIGNAL 1 ? PROPEP ? 154 /FTId=PRO_0000002055 CHAIN 155 308 Apolipoprotein F /FTId=PRO_0000002056 SEQUENCE 308 AA; 33842 MW; 490B55D6A3692F46 CRC64; MGAQLLTCTV SDSIRHQFSC FATSCCVLWV PKGVSTMLPP SQLGSQPPTS DPLSCQALLP RSLPGFTHMP PLSKFLVGLA LRNALEEAGC WADVWALQLQ LYRFGGVEAT QALIRHLQEL QKGGRADWKV SVNALSSALQ LLAWEQAGPK RVKRSLSNMG CENEQEQRVH NVVELLPAVG TYYNLGTALY YAIKNCTDKA KERGRDGAID LGYDLLMTMV GMSGGPTGAV ITAALKPALK AGVQRLIRYY HDEEGVTTSQ PETRKDAPTY RDDVEETTMS NLVSEVESTT SNWGRPLLKN YVFLAYKR|
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