|Other Accession||NM_001168693, NP_001162164|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat|
|Alias Symbol||Pp11r, Tcl-30|
|Other Names||Poly(U)-specific endoribonuclease, 3.1.-.-, Placental protein 11-related protein, PP11-related protein, Protein endoU, T-cell-specific protein 30, Tcl-30, Uridylate-specific endoribonuclease, Endou, Pp11r|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Endou antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Endou antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.|
|Tissue Location||Specifically expressed in T-cells during apoptosis. Expressed in surface heat stable antigen (HSA)- containing T-cells populations (CD4(-)CD8(-)HSA(+), CD4(+)CD8(-)HSA(+), CD4(-)CD8(+)HSA(+), and CD4(+)CD8(+)HSA(+)) and not in the HSA(-) single positive T-cell populations of the thymus or spleen, suggesting that expression is lost during T-cell maturation and is absent at the most mature stages of T-cell development.|
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