|Other Accession||NM_013402, NP_037534|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Chicken, Bovine, Dog|
|Alias Symbol||D5D, FADS6, FADSD5, FLJ38956, FLJ90273, LLCDL1, TU12|
|Other Names||Fatty acid desaturase 1, 1.14.19.-, Delta(5) fatty acid desaturase, D5D, Delta(5) desaturase, Delta-5 desaturase, FADS1, FADSD5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FADS1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FADS1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.|
|Cellular Location||Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein Mitochondrion|
|Tissue Location||Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.|
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Provided below are standard protocols that you may find useful for product applications.
Rzehak,P., (er) Br. J. Nutr., 1-7 (2008) In pressReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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