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FGD1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P98174 |
| Other Accession | NM_004463, NP_004454 |
| Reactivity | Human, Rat, Pig, Bovine |
| Predicted | Human, Rabbit, Pig, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 106kDa |
| Gene ID | 2245 |
|---|---|
| Alias Symbol | AAS, FGDY, ZFYVE3, MRXS16 |
| Other Names | FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein, Rho/Rac guanine nucleotide exchange factor FGD1, Rho/Rac GEF, Zinc finger FYVE domain-containing protein 3, FGD1, FGDY, ZFYVE3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-FGD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | FGD1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FGD1 |
|---|---|
| Synonyms | FGDY, ZFYVE3 |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Cellular Location | Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle Cytoplasm, cytoskeleton. Note=Associated with membrane ruffles and lamellipodia. |
| Tissue Location | Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Bottani,A.,(2007)Am.J.Med.Genet.A143A(19),2334-2338ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.Publications:Zou,W.etal.MLK3regulatesbonedevelopmentdownstreamofthefaciogenitaldysplasiaproteinFGD1inmice.J.Clin.Invest.121,4383-92(2011).WB,Human,Bovine,Pig,Rat21965325
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