|Other Accession||NM_004463, NP_004454|
|Reactivity||Human, Rat, Pig, Bovine|
|Predicted||Human, Rabbit, Pig, Bovine, Dog|
|Alias Symbol||AAS, FGDY, ZFYVE3, MRXS16|
|Other Names||FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein, Rho/Rac guanine nucleotide exchange factor FGD1, Rho/Rac GEF, Zinc finger FYVE domain-containing protein 3, FGD1, FGDY, ZFYVE3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FGD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FGD1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.|
|Cellular Location||Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton Note=Associated with membrane ruffles and lamellipodia|
|Tissue Location||Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle|
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