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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > RAB38 antibody - N-terminal region
RAB38 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P57729 |
| Other Accession | NM_022337, NP_071732 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Chicken, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24kDa |
| Gene ID | 23682 |
|---|---|
| Alias Symbol | NY-MEL-1, rrGTPbp |
| Other Names | Ras-related protein Rab-38, Melanoma antigen NY-MEL-1, RAB38 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RAB38 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RAB38 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAB38 |
|---|---|
| Function | May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome membrane Note=Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991) |
| Tissue Location | Expressed in melanocytes. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Wang,F.,(2008)Biochem.Biophys.Res.Commun.372(1),162-167ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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$ 389.00
Cat# AI12126
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