|Other Accession||NM_032527, NP_115916|
|Alias Symbol||GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP, RP4-583P15.3|
|Other Names||Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6, Zinc finger CCCH domain-containing protein 9, Zinc finger and G patch domain-containing protein, ZGPAT, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ZGPAT antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZGPAT antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC|
|Function||Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.|
|Tissue Location||Widely expressed.|
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