Alx1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8C8B0 |
Other Accession | NM_172553, NP_766141 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig |
Predicted | Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37kDa |
Gene ID | 216285 |
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Alias Symbol | AI314867, C130005I02, Cart1 |
Other Names | ALX homeobox protein 1, Cartilage homeoprotein 1, CART-1, Alx1, Cart1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Alx1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Alx1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Alx1 {ECO:0000312|MGI:MGI:104621} |
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Function | Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:12929931). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival (PubMed:8673125). May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 (By similarity). |
Cellular Location | Nucleus. |
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