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Fbxo2 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Fbxo2 antibody - C-terminal region AI12221

    WB Suggested Anti-Fbxo2 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Small Intestine
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q80UW2
Other Accession NM_176848, NP_789818
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Additional Information
Gene ID 230904
Alias Symbol FBG1, FBX2, Fbs1, Fbs2, MGC54895, NFB42, Prpl4
Other Names F-box only protein 2, Fbxo2, Fbs1, Fbx2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Fbxo2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFbxo2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fbxo2
Synonyms Fbs1, Fbx2
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
Cellular Location Cytoplasm. Microsome membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Detected in brain and cochlea, in epithelial support cells and hair cells of the organ of Corti (at protein level).
Research Areas
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$ 293.00
Cat# AI12221
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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