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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RNF169 antibody - N-terminal region   

RNF169 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - RNF169 antibody - N-terminal region AI12287

    WB Suggested Anti-RNF169 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NCN4
Other Accession NM_001098638, NP_001092108
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 77kDa
Additional Information
Gene ID 254225
Alias Symbol KIAA1991
Other Names E3 ubiquitin-protein ligase RNF169, 6.3.2.-, RING finger protein 169, RNF169, KIAA1991
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RNF169 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRNF169 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF169
Synonyms KIAA1991
Function Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin- protein ligase activity is not required for regulation of DSBs repair.
Cellular Location Nucleus, nucleoplasm. Note=Localizes to sites of double- strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products
Research Areas
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$ 293.00
Cat# AI12287
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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