|Other Accession||NM_011933, NP_036063|
|Reactivity||Human, Mouse, Rat, Horse, Yeast, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Pig, Chicken, Guinea Pig, Dog|
|Other Names||Peroxisomal 2, 4-dienoyl-CoA reductase, 188.8.131.52, 2, 4-dienoyl-CoA reductase 2, Decr2, Pdcr|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Decr2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Decr2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.|
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