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SLC9A3 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P48764 |
| Other Accession | NM_004174, NP_004165 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Sheep, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 93kDa |
| Gene ID | 6550 |
|---|---|
| Alias Symbol | MGC126718, MGC126720, NHE3 |
| Other Names | Sodium/hydrogen exchanger 3, Na(+)/H(+) exchanger 3, NHE-3, Solute carrier family 9 member 3, SLC9A3, NHE3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC9A3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SLC9A3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC9A3 (HGNC:11073) |
|---|---|
| Function | Plasma membrane Na(+)/H(+) antiporter (PubMed:26358773, PubMed:35613257, PubMed:18829453). Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis (By similarity). Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation (PubMed:26358773, PubMed:24622516). |
| Cellular Location | Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Note=In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane Angiotensin-2 enhances apical expression (By similarity) {ECO:0000250|UniProtKB:Q28362} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12337
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