|Other Accession||NM_001013579, NP_001013597|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Bovine, Guinea Pig, Dog|
|Alias Symbol||AWAT1, DGA2, DGAT2L3|
|Other Names||Acyl-CoA wax alcohol acyltransferase 1, 184.108.40.206, Diacylglycerol O-acyltransferase 2-like protein 3, Diacylglycerol acyltransferase 2, Long-chain-alcohol O-fatty-acyltransferase 1, AWAT1, DGA2, DGAT2L3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-AWAT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||AWAT1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis|
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