USP48 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q86UV5 |
Other Accession | NM_001032730, AAH67261 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70kDa |
Gene ID | 84196 |
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Alias Symbol | USP31, RAP1GA1 |
Other Names | Ubiquitin carboxyl-terminal hydrolase 48, 3.4.19.12, Deubiquitinating enzyme 48, Ubiquitin thioesterase 48, Ubiquitin-specific-processing protease 48, USP48, USP31 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-USP48 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | USP48 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | USP48 |
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Synonyms | USP31 |
Function | Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (PubMed:16214042, PubMed:34059922). May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | Widely expressed. Expressed in the fetal inner ear (PubMed:34059922). |
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