|Other Accession||NM_007984, NP_032010|
|Reactivity||Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Zebrafish, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||AI663989, Fan1, fascin-1|
|Other Names||Fascin, Singed-like protein, Fscn1, Fan1, Snl|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Fscn1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Fscn1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, invadopodium. Cytoplasm, cytosol Note=In glioma cells, partially colocalizes with F-actin stress fibers in the cytosol.|
|Tissue Location||Most abundant in brain. Found in other tissues including uterus, small intestine and spleen|
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