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SMC4 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - SMC4 antibody - middle region AI12658

    WB Suggested Anti-SMC4 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: MCF7 cell lysate
    There is BioGPS gene expression data showing that SMC4 is expressed in MCF7
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NTJ3
Other Accession NM_001002800, NP_001002800
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Horse, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 147kDa
Additional Information
Gene ID 10051
Alias Symbol CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Other Names Structural maintenance of chromosomes protein 4, SMC protein 4, SMC-4, Chromosome-associated polypeptide C, hCAP-C, XCAP-C homolog, SMC4, CAPC, SMC4L1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SMC4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSMC4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMC4
Synonyms CAPC, SMC4L1
Function Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Cellular Location Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase
Tissue Location Widely expressed. Higher expression in testis, colon, thymus.
Research Areas
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$ 293.00
Cat# AI12658
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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