|Other Accession||NM_003999, NP_003990|
|Reactivity||Human, Rabbit, Horse, Guinea Pig, Dog|
|Predicted||Human, Rabbit, Horse, Guinea Pig, Dog|
|Alias Symbol||MGC150626, MGC150627, MGC75127, OSMRB, PLCA1|
|Other Names||Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, OSMR, OSMRB|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-OSMR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||OSMR antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines.|
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