|Application ||WB, IHC|
|Other Accession||NM_007076, NP_009007|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||HYPE, MGC5623, UNQ3041, hip13, HIP13|
|Other Names||Adenosine monophosphate-protein transferase FICD, 2.7.7.n1, AMPylator FICD, FIC domain-containing protein, Huntingtin yeast partner E, Huntingtin-interacting protein 13, HIP-13, Huntingtin-interacting protein E, FICD, HIP13, HYPE|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FICD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FICD antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.|
|Cellular Location||Membrane; Single-pass membrane protein|
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