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Rabbit Polyclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | P22310 |
| Other Accession | NM_007120, NP_009051 |
| Reactivity | Human |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57kDa |
| Gene ID | 54657 |
|---|---|
| Alias Symbol | HUG-BR2, UDPGT, UGT1D, UGT-1D, UGT1.4, UGT1-04, UDPGT 1-4 |
| Other Names | UDP-glucuronosyltransferase 1-4, UDPGT 1-4, UGT1*4, UGT1-04, UGT1.4, 2.4.1.17, Bilirubin-specific UDPGT isozyme 2, hUG-BR2, UDP-glucuronosyltransferase 1-D, UGT-1D, UGT1D, UDP-glucuronosyltransferase 1A4, UGT1A4, GNT1, UGT1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-UGT1A4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | UGT1A4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UGT1A4 |
|---|---|
| Synonyms | GNT1, UGT1 |
| Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). |
| Cellular Location | Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein |
| Tissue Location | Isoform 1 and isoform 2 are expressed in liver, kidney, colon and small intestine. Isoform 2 but not isoform 1 is expressed in esophagus. Not expressed in skin |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Kaku,T.,(2004)Biochem.Pharmacol.67(11),2093-2102ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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