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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Bmp10 antibody - N-terminal region
Bmp10 antibody - N-terminal region
Rabbit Polyclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | Q4AEG6 |
| Other Accession | NM_001031824, NP_001026994 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48kDa |
| Gene ID | 500245 |
|---|---|
| Alias Symbol | Bmp10 |
| Other Names | Bone morphogenetic protein 10, BMP-10, Bmp10 {ECO:0000312|EMBL:BAE16990.1, ECO:0000312|RGD:1562986} |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Bmp10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Bmp10 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Bmp10 {ECO:0000312|EMBL:BAE16990.1, ECO:0000312|RGD:1562986} |
|---|---|
| Function | Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P12643}. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI12739
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